What is EPO and Why Many Cyclists Use it For Doping
Erythropoietin (EPO) is a hormone produced by the kidney that promotes methandienone dianabol the formation of red blood cells by the bone marrow. It can be measured and detected in the blood by means of a test, and it is thanks to it that we realize that many cyclists use it. However, is it the fault of the cyclists or is it that competitions like the Tour de France are too tough and demanding to need extra help? This is a question we ask ourselves both in these cases and in competitive bodybuilding, in which the use of steroids is more than proven.
Renal cells that produce erythropoietin are sensitive to low levels of oxygen in the blood that travels through the kidney. These cells produce and release erythropoietin when the oxygen level is too low. A low oxygen level may indicate a decrease in the number of red blood cells (anemia) or hemoglobin molecules that carry oxygen through the body.
Why our body needs EPO (or why we generate it)
Erythropoietin stimulates the bone marrow to make more red blood cells . The resulting increase in red blood cells increases the oxygen carrying capacity of the blood. Among its main functions is the development of red blood cells, the start of the synthesis of hemoglobin, the molecule that is inside red blood cells and that transports oxygen, and chemically, erythropoietin is a protein with an attached sugar (a glycoprotein). It is one of several similar glycoproteins that serve as stimulants for the growth of specific types of blood cells in the bone marrow.
The Lance Armstrong case
Deep in our hearts we knew it, but until the words came out of his mouth, there was a ray of hope that he could still be one of the great heroes. When he admitted that he had been doped on steroids and erythropoietin (EPO), he showed some contempt for those around him, friends and enemies . The problem, however, is that high-competition sports are always full of cheats, and the public accepts some acts of dishonesty as part of the game. The distinction between what is ethically acceptable and what is not remains a fine line.
Why cyclists use EPO
Muscle cells are factories that take raw materials, oxygen and glucose, and convert them into energy. Training increases the body's ability to deliver oxygen to cells and increases muscle size. More efficiency and more power produce better sports performance. Increasing the number of red blood cells in the body increases the ability to deliver oxygen to the tissues and that is where blood doping and EPO come in.
In principle, it is indicated for anemia
Using recombinant DNA technology, erythropoietin has been synthetically produced for use as a treatment for people with certain types of anemia . Erythropoietin can be used to correct anemia by stimulating the production of red blood cells in the bone marrow under boldenone undecylenate in Deutschland online kaufen these conditions. The medicine is known as epoetin alfa (Epogen, Procrit) or darbepoietin alfa (Arnesp). It can be administered as an intravenous injection (into a vein) or subcutaneously (under the skin).
Erythropoietin is used in many clinical settings . The most common use is in people with anemia related to kidney dysfunction. When the kidneys are not working properly, they make less than the normal amount of erythropoietin, which can lead to low red blood cell production or anemia . Therefore, by replacing erythropoietin with an injection of synthetic erythropoietin, anemia related to kidney disease can be treated. Epogen or Procrit is currently a standard part of therapy in kidney disease patients requiring dialysis to treat and prevent anemia.